Fecundity genes in sheep
WebJun 7, 2024 · The present results confirmed that the genetic variants of the GDF9 gene were considered to be the major gene markers for enhancement of the prolificacy in … WebUtilize the information on sheep breeding, including determining the most efficient ewe size, preparing for the breeding season, improving newborn lamb survival, and accelerated …
Fecundity genes in sheep
Did you know?
WebDec 1, 2024 · Fecundity critically affects the profitability of sheep production, but the genetic mechanism of high-prolificacy is still unclear in sheep. We identified potential signaling pathways and differentially abundant proteins associated with reproductive performance through a combination of sheep uterus tissues proteome and transcriptome … WebDec 21, 2001 · The Inverdale fecundity gene, FecX, was identified in a prolific New Zealand sheep family descended from a Romney female that produced 33 lambs in 11 lambings . Progeny testing suggested that a major gene for prolificacy was located on the X …
WebJul 1, 2024 · The Booroola fecundity ( FecBB) mutation (g.A746G, p.Q249R) in the bone morphogenetic protein receptor 1B ( BMPR1B) gene influences fecundity in many sheep breeds. In this study, by using ABEmax we successfully obtained lambs with defined point mutations that result in an amino acid substitution (p.Gln249Arg). WebDec 19, 2024 · In the past, it has been reported that mutations in the Booroola fecundity ( FecB) gene associated with sheep reproduction lead to the inactivation of the BMPR1B protein and impair BMP signaling, thereby regulating ovarian granulosa cell differentiation, increasing ovulation rate and litter size ( 6, 7 ).
WebSep 26, 2013 · Prolific sheep have proven to be a valuable model to identify genes and mutations implicated in ovarian function and female fertility. Indeed, fecundity genes of the Bone Morphogenetic Protein (BMP) … WebOct 13, 2024 · Fecundity gene SNPs as informative markers for assessment of Indian goat genetic architecture. Indian J Anim Sci. 50: 349 – 356. [Google Scholar] Nawaz A, Masroor K, Babar E, Nadeem A, Hussain T, Bilal F, Javed K, Muhammad K. 2013. Identification of molecular markers in bone morphogenetic protien15 (BMP15) gene of Balochi sheep. …
WebGenetic polymorphism of the GDF9 gene. The PCR products of the GDF9 (FecG H) gene digested with DdeI are shown in Figure 1. The results for genotype AB found that all sheep breeds showed mutations in which the …
Web@article{Tian2024WholeGS, title={Whole genome sequencing identified candidate genes related to litter size of Qinghai fine wool sheep under artificial selection}, author={Dehong Tian and Buying Han and Quanbang Pei and Baicheng Zhou and Lei Wang and Xuejin Li and Kai Zhao}, journal={Small Ruminant Research}, year={2024} } driving test centre redhillWebMay 14, 2001 · The Booroola fecundity gene was named FecB by the Committee on Genetic Nomenclature of Sheep and Goats. The effect of the FecB mutation is additive for ovulation rate (the number of ova shed at each ovulatory cycle) and partially dominant for litter size. On average, one copy of the FecB mutation increases litter size by 1 extra lamb. driving test centre routes scunthorpeWebMay 20, 2024 · Small-tailed Han sheep, with different FecB genotypes, manifest distinct ovulation rates and fecundities, which are due to differences in reproductive hormones secreted by the hypothalamic-pituitary-ovarian axis. Nevertheless, the function of the hypothalamus against a FecB mutant background on increasing ovulation rate is rarely … driving test centre portsdown hillWebApr 12, 2006 · The expression of the three fecundity genes has been observed in the sheep ovary. Oocytes are the only sources of GDF-9 and BMP-15 [].The BMP receptor BMPR-1B is expressed by granulosa cells and oocytes from the primary to the late antral follicle stages (Fig. 1), and to a lesser extent, by the theca layer of ovine and bovine … driving test centre salisburyWebFecundity genes in sheep. Since 1980 there has been increasing interest in the identification and utilisation of major genes for prolificacy in sheep. Mutations that increase ovulation rate have been discovered in the BMPR-1B, BMP15 and GDF9 genes, and others are … driving test centres edinburghWebNov 1, 2024 · The Booroola fecundity gene ( FecB) increases ovulation rate and litter size in sheep and is inherited as a single autosomal locus (Wilson et al, 2001 ). GDF9 plays an important role in controlling ovarian physiology and enhancing oocyte developmental competence (Stocker et al., 2024 ). driving test centres bradfordWebApr 12, 2024 · Recently, increasing attention has been paid to sheep milk products, which are high in saturated fatty acids (SFA), and the extent of their impact on human health. This study aimed to identify SNPs for PI, PIII, and Exon 53 in the ACACα gene and their association with the MC and FA profiles in Najdi sheep milk. A total of 76 multiparous … driving test centres buckinghamshire