Fosphenytoin max dose
WebIM or IN 0.2 mg/kg Maximum 10 mg/dose IV OR IO 0.1 mg/kg Maximum 5 mg/dose Repeat as needed every 3-5 minutes if seizure continues General Principles 1. Remember A ’s 2. Get a good history and description from a witness 3. Determine time of onset of seizure and whether this is a seizure 4. Follow sequence of benzodiazepine, fosphenytoin, Loading dose: 15 to 20 mg PE/kg IV; infuse at 100 to 150 mg PE/min 1. Maximum infusion rate: 150 mg PE/min 1. After initial maintenance dose, subsequent doses should be individualized to achieve therapeutic phenytoin concentrations 1. The maximal rate of IV administration should not be exceeded due to … See more Loading dose: 10 to 20 mg PE/kg IV; infuse at a rate no greater than 150 mg PE/min 1. May be administered as a single IM dose when IV access is impossible 1. After initial … See more Cerebyx: Less than 17 years: Loading Dose: 10 to 15 mg PE/kg IV; infuse at 1 to 2 mg PE/kg/min or 150 mg PE/min, whichever is slower Maintenance Doses: 1. Initial Maintenance … See more Cerebyx: Less than 17 years: Loading dose: 15 to 20 mg PE/kg IV; infuse at 2 mg PE/min (or 150 mg PE/min, whichever is slower) Maintenance Dose: 1. Initial Maintenance Dose: 2 … See more Use with caution; monitor unbound phenytoin concentrations Severe Renal Impairment (eGFR 15 to 29 mL/min/1.73 m2): 1. Sesquient: Closely monitor serum creatinine levels; if … See more
Fosphenytoin max dose
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WebOct 10, 2013 · Administer 20 mg/Kg fosphenytoin intravenously up to a maximum dose of 1500 mg ( 75 Kg) over 10 minutes. Those weighing more than 75 Kg receive a fixed … WebJul 4, 2024 · The maximum concentration of fosphenytoin sodium injection in any solution should be 25 mg PE/mL. When fosphenytoin sodium injection is given as an IV infusion, fosphenytoin sodium injection needs to be diluted and should only be administered at a rate not exceeding 150 mg PE/min.
WebJul 4, 2024 · The maximum concentration of fosphenytoin sodium injection in any solution should be 25 mg PE/mL. When fosphenytoin sodium injection is given as an IV … Webmaximum plasma fosphenytoin concentrations are achieved at the end of the infusion. Fospheny-toin has a half-life of approximately 15 minutes. Intramuscular:Fosphenytoin is completely bioavail-able following IM administration of fosphenytoin sodium. Peak concentrations occur at approxi-mately 30 minutes post dose. Plasma fosphenytoin
WebStatus epilepticus: 20 mg PE/kg IV (max. dose: 1500 mg PE/dose) Nonemergent loading: 10–20 mg PE/kg IV/IM. Nonemergent initial maintenance dose ... Fosphenytoin is administered in phenytoin equivalents (PE). The usual loading dose of fosphenytoin is 15-20 PE/kg administered over 30 min. Maintenance doses of 4-8 PE/kg/day can be given. … WebInitial Maintenance Dosage: 4 mg PE/kg/day to 6 mg PE/kg/day in divided doses: Not to exceed a maximum rate of 150 mg PE/min: Pediatric (Birth to less than 17 years of age) …
WebThe weight-based infusion rate provided levetiracetam at a dose of 60 mg per kilogram (maximum, 4500 mg), fosphenytoin at a dose of 20 mgPE per kilogram (maximum, 1500 mgPE), or valproate at a ...
Web300 mg/day PO initially; may titrate to 1800-2400 mg/day maximum. Diabetic Neuropathy (Off-label) 150-300 mg/day PO initially; may increase to 900-1200 mg/day (general recommendation) ... fosphenytoin. oxcarbazepine will increase the level or effect of fosphenytoin by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. computer pawn sgop njWebJan 17, 2024 · Prior to intravenous (IV) infusion, dilute fosphenytoin sodium injection in 5% dextrose or 0.9% saline solution for injection to a concentration ranging from 1.5 to 25 mg PE/mL. The maximum concentration of fosphenytoin sodium in … computer pawn shop bend oregonWebNov 30, 2024 · This agent is arguably levetiracetam (and definitely not fosphenytoin). Large doses of levetiracetam were used in this study (60 mg/kg, up to a maximal dose of 4.5 grams IV). This same exact dose … computer pawn rentonWebProphylaxis or treatment of seizures associated with neurosurgery or head injury. Initially 10–15 mg (PE)/kg, then 4–5 mg (PE)/kg daily in 1–4 divided doses, dose to be administered at a rate of 1–2 mg (PE)/kg/minute, maximum 100 mg (PE)/minute, dose to be adjusted according to response and trough plasma-phenytoin concentration. ecoflame north eastWebJul 6, 2024 · Consider checking a post-load antiseizure medication level in some cases (for fosphenytoin ... If still seizing, may give an additional 5 mg/kg (max 250 mg) or simply 200 mg, over 5 minutes. (33896531; 29733464) Maintenance: Typically 200 mg IV q12hr. However the dose range may extend up to 600 mg/day, divided q12hr or q6hr. computer pawnWebDrug Route Dosage Max Dose Supplemental Dose Lorazepam IV 0.1 mg/kg 5 mg/dose Midazolam IV/IM 0.2 mg/kg 10 mg/dose IN/Buc 0.3 mg/kg Diazepam IV 0.2 mg/kg 10 mg/dose Rectal 0.5 mg/kg 20 mg/dose Fosphenytoin IV 20 mg/kg 10 mg/kg Levetiracetam IV 40 mg/kg 20 mg/kg Phenobarbital IV 20 mg/kg Valproic acid IV 20 mg/kg computer pawn near meWebMay 26, 2024 · Initial loading dose: 20 mg/kg. Mini-loading dose (for subtherapeutic levels): 10 mg/kg. Maintenance dose: 5 - 7 mg/kg/day … ecoflame birmingham